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DeCS
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Descriptor English:
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Mannose-Binding Protein-Associated Serine Proteases
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Descriptor Spanish:
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Serina Proteasas Asociadas a la Proteína de Unión a la Manosa
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Descriptor Portuguese:
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Serina Proteases Associadas a Proteína de Ligação a Manose
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Synonyms English:
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MASP Proteases
MASP Related Protein
MASP-Related Protein
MASPs
MBL Associated Serine Proteases
MBL-Associated Serine Proteases
MBP Associated Serine Protease
MBP Associated Serine Protease Related Protein
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein
Mannan Binding Lectin Serine Proteases
Mannan-Binding Lectin Serine Proteases
Mannose Binding Protein Associated Serine Protease
Mannose-Binding Protein-Associated Serine Protease
Proteases, MASP
Protein, MASP-Related
Serine Protease, MBP-Associated
Serine Proteases, MBL-Associated
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Tree Number:
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D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
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Definition English:
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Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE. |
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Indexing Annotation English:
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see SCR for organism-specific terms
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Pharmacological Action:
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Immunologic Factors
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History Note English:
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2006 (1994)
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Allowable Qualifiers English:
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Record Number:
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50582
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Unique Identifier:
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D050606
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Occurrence in VHL:
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Similar:
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DeCS
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